Familial Down syndrome is similar to primary Down syndrome in that it is caused by trisomy 21….
Familial Down syndrome is similar to primary Down syndrome in that it is caused by trisomy 21. However, in familial Down syndrome, all or part of the third copy of chromosome 21 has translocated onto another autosome, typically chromosome 14. In cases of familial Down syndrome, one of the parents of the affected child is often a carrier of a translocated chromosome. The translocation carrier parent dodes not have Down syndrome because he or she has a total of two copies of chromosome 21. Suppose that a woman is a translocation carrier of the chromosome 21 on chromosome 14. She concieves six
Familial Down syndrome is similar to primary Down syndrome in that it is caused by trisomy 21. However, in familial Down syndrome, all or part of the third copy of chromosome 21 has translocated onto another autosome, typically chromosome 14. In cases of familial Down syndrome, one of the parents of the affected child is often a carrier of a translocated chromosome. The translocation carrier parent dodes not have Down syndrome because he or she has a total of two copies of chromosome 21. Suppose that a woman is a translocation carrier of the chromosome 21 on chromosome 14. She concieves six zygotes with a normal man who carries no aneuploidies. Match the description of the chromsomes inherited by each zygote with the viability of the zygote.
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