POGIL 5: Enzyme Catalysis Part I: Warm Up (12 minutes) Almost every chemical reaction that occurs in

POGIL 5: Enzyme Catalysis Part I: Warm Up (12 minutes) Almost every chemical reaction that occurs in a living thing is catalyzed by an enzyme. The purpose of this exercise is for you to: 1) get a better understanding of the principles of catalysis; 2) gain experience and practice drawing and interpreting reaction coordinate diagrams; and 3) developing a better understanding of how enzymes behave as catalysts. Try to answer questions 1-4 without consulting notes, books, etc. Use each other’s knowledge 1. With respect to catalysis of chemical reactions, what are some ways that enzyme catalysts

»POGIL 5: Enzyme Catalysis Part I: Warm Up (12 minutes) Almost every chemical reaction that occurs in a living thing is catalyzed by an enzyme. The purpose of this exercise is for you to: 1) get a better understanding of the principles of catalysis; 2) gain experience and practice drawing and interpreting reaction coordinate diagrams; and 3) developing a better understanding of how enzymes behave as catalysts. Try to answer questions 1-4 without consulting notes, books, etc. Use each other’s knowledge 1. With respect to catalysis of chemical reactions, what are some ways that enzyme catalysts differ from small molecule catalysts? 2. In terms of the thermodynamics of chemical reactions, how are enzymes and small molecule catalysts alike? 3. In terms of reaction rates and equilibrium constants, how do catalysts affect chemical reactions? 4. The table below contains some experimental data for a reaction between reagents A and B. The reaction rates were measured in seconds. Rate [A] (MM) [B] (MM) 10 10 15 10 10 15 100 100 150 a. What order reaction is this? take-out order zero order first order second order b. What would be appropriate units for the rate constant for this reaction? c. What would be appropriate units for the rate of this reaction?

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